Manufacturing genomic medicines is cumbersome, but new techniques using donated cells are more scalable and could slash production costs by 95%, potentially facilitating broader adoption.1
Recent regulatory approvals have helped genomic medicines gain momentum. Sales of genomic medicines are forecast to increase at a 39% compound annual growth rate from 2024-2030.2
GNOM provides global exposure to emerging areas within the Health Care sector, at the intersection of science and technology.
1International Society for Cell and Gene Therapy, Feb 2019
2Evaluate Pharma, n.d., Technology Overviews of: Cell Therapy, Gene Therapy, Gene-Modified Cell Therapy, and Genome Editing, all accessed 1 Nov 2024
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* The financial statements include the Fund’s disclosures required by Items 7 through 11 of Form N-CSR, which includes the financial statements, financial highlights, and other important information when applicable.
** The financial statements include the Fund’s disclosures required by Items 7 through 11 of Form N-CSR, which includes the financial statements, financial highlights, and other important information when applicable.
VERSUS | BETA |
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S&P 500 | 1.29 |
NASDAQ-100 | 0.98 |
MSCI EAFE | 1.01 |
MSCI Emg. Mkts | 0.78 |
Standard Deviation | 28.80% |
NAV | $7.98 | Daily Change | $0.15 | 1.92% |
Market Price | $7.98 | Daily Change | $0.16 | 2.05% |
Return on Equity | -29.80% | |
Weighted Avg. Market Cap | 15,996 M | |
2024 | 2025 | |
Price-to-earnings | -9.28 | -11.08 |
Price-to-book value | 2.86 | 3.89 |
Net Assets (%) | Ticker | Name | SEDOL | Market Price ($) | Shares Held | Market Value ($) |
---|---|---|---|---|---|---|
5.00 | ALNY | ALNYLAM PHARMACE | B00FWN1 | 291.68 | 7,221 | 2,106,221.28 |
4.58 | ILMN | ILLUMINA INC | 2613990 | 84.21 | 22,914 | 1,929,587.94 |
4.37 | MRNA | MODERNA INC | BGSXTS3 | 27.99 | 65,832 | 1,842,637.68 |
4.31 | NTRA | NATERA INC | BYQRG48 | 154.53 | 11,761 | 1,817,427.33 |
4.28 | RNA | AVIDITY BIOSCIENCES INC | BMWHPY1 | 31.64 | 56,949 | 1,801,866.36 |
4.22 | CRSP | CRISPR THERAPEUTICS AG | BDHF4K6 | 39.25 | 45,334 | 1,779,359.50 |
4.18 | QGEN | QIAGEN N.V. | BS2CPH1 | 42.70 | 41,285 | 1,762,869.50 |
4.15 | RARE | ULTRAGENYX PHARM | BJ62Z18 | 37.35 | 46,829 | 1,749,063.15 |
4.09 | TECH | BIO-TECHNE CORP | BSHZ3Q0 | 49.53 | 34,832 | 1,725,228.96 |
4.01 | BMRN | BIOMARIN PHARMAC | 2437071 | 59.93 | 28,208 | 1,690,505.44 |
Industry | Weight (%) | |
---|---|---|
Pharmaceuticals, Biotechnology & Life Sciences | 98.6 | |
Health Care Equipment & Services | 1.0 | |
Pharmaceuticals, Biotechnology | 0.4 |
Source: AltaVista Research, LLC
All Sector, Industry and Geographic breakdowns, where provided, are based on equity positions held by the ETF and exclude cash, currencies, and other holdings.
Fund NAV | Market Price | Index | |
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1 Year | -29.31% | -30.14% | -28.88% |
3 Years | -18.84% | -19.13% | -18.39% |
5 Years | -8.64% | -8.81% | -8.17% |
Since Inception | -10.16% | -10.03% | -9.68% |
Performance is shown on a total return basis (i.e., with gross income reinvested, where applicable). Cumulative return is the aggregate amount that an investment has gained or lost over time. Annualized return is the average return gained or lost by an investment each year over a given time period.
The performance data quoted represents past performance. Past performance does not guarantee future results. The investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than their original cost and current performance may be lower or higher than the performance quoted. High short-term performance, when observed, is unusual and investors should not expect such performance to be repeated.